NAD Therapy

What You Need to Know About This Cellular Coenzyme and Reproductive Health

Fertility is a deeply personal journey—and often a complex one, especially as we age. While there are many factors that influence reproductive health, emerging research suggests that maintaining and restoring NAD+ (Nicotinamide Adenine Dinucleotide) levels may play a role in improving both egg and sperm quality.

At Femma Clinic, we offer non-invasive wellness support for women and couples looking to optimize fertility naturally, including NAD+ injections under our intravenous therapy program in Mont Kiara. In this article, we’ll explore the science behind NAD+, its connection to reproductive health, and whether NAD+ therapy could support your fertility goals.

What Is NAD+?

NAD+ is a coenzyme present in every cell in the body. It’s essential for:

• Energy metabolism (mitochondrial function)

• DNA repair and stability

• Cell signaling and healthy aging

As we age, NAD+ levels naturally decline—contributing to reduced cellular function, fatigue, and even fertility decline. For women, this often means lower egg quality and mitochondrial dysfunction in oocytes. For men, this decline is linked to reduced sperm motility and increased oxidative stress.

How NAD+ Decline Affects Fertility

In women, age-related NAD+ decline can reduce the energy efficiency of egg cells, affecting their ability to mature, be fertilized, and support a healthy pregnancy. Without sufficient NAD+, egg cells become more susceptible to DNA damage and oxidative stress—both major contributors to age-related fertility decline.

In men, NAD+ also plays a role in supporting sperm motility and morphology. Low NAD+ levels can impact testosterone regulation, increase oxidative damage, and impair overall sperm health.

What the Research Says

Several preclinical studies suggest that boosting NAD+ levels can improve reproductive function:

• NAD+ Restores Egg Quality

  A landmark study published in Cell Reports showed that supplementing aged female mice with NMN (a precursor to NAD+) significantly improved egg quality and increased the number of live births. (PMC7063679)

• Improved Mitochondrial Function in Oocytes

  Additional findings show that NAD+ supplementation improves mitochondrial activity in aging eggs, leading to healthier embryo development and improved fertility outcomes.

• Sperm Health and NAD+

  While limited, research also indicates that NAD+ protects sperm cells from oxidative stress, potentially improving motility, morphology, and fertility outcomes.

How NAD+ May Support Fertility

For Women:

✓ Enhances mitochondrial energy in egg cells

✓ Promotes DNA repair in aging oocytes

✓ Reduces oxidative stress

✓ Improves egg quality and reproductive potential

For Men:

✓ Supports sperm motility and morphology

✓ Reduces oxidative damage to sperm

✓ Helps maintain reproductive hormone balance

How to Increase NAD+ Naturally

While NAD+ declines with age, the following lifestyle interventions may support its natural production:

• Diet: Include niacin-rich foods (chicken, tuna, mushrooms) and tryptophan-based proteins.

• Exercise: Moderate-intensity workouts can stimulate NAD+ production.

• Intermittent Fasting: Can activate longevity pathways that naturally boost NAD+ synthesis.

NAD+ Therapy at Femma Clinic – Mont Kiara

If you’re looking for a more targeted solution, Femma Clinic offers safe and effective NAD+ Injections as part of our intravenous therapy suite. These injections help restore cellular energy, combat oxidative stress, and potentially support your fertility wellness goals.

We currently do not use NAD+ patches or oral supplements, as IV-based and injectable options allow for faster, more controlled absorption—administered under medical supervision.

Is NAD+ Right for You?

While NAD+ therapy is not a replacement for fertility treatment, it can be a helpful complementary approach—especially for women over 30 looking to support egg quality, or men experiencing reduced sperm health.

Our team at Femma Clinic will work closely with you to assess your reproductive health and determine whether NAD+ supplementation fits into your personalized fertility plan.